解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Haploid nuclear DNA of 23 species of Aedes, as determined by Feulgen cytophotometry, was found to vary 3-fold. This was accompanied by a 2-fold variation in total chromosomal length. There was a significant correlation (r = 0.765, P less than 0.001) between these two parameters. Genome size varied from 0.87 pg to 1.3 ...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1987.120
更新日期:1987-10-01 00:00:00
abstract::The hypothesis that traits closely associated with fitness will generally possess lower heritabilities than traits more loosely connected with fitness is tested using 1120 narrow sense heritability estimates for wild, outbred animal populations, collected from the published record. Our results indicate that life histo...
journal_title:Heredity
pub_type: 杂志文章,评审
doi:10.1038/hdy.1987.113
更新日期:1987-10-01 00:00:00
abstract::Genetic segregation was studied in more than 1900 seedlings of an F2 between the maize (Zea mays L.) inbred lines T232 and CM37. Significant segregation distortion was observed at 11 of 17 segregating allozyme loci and at a single morphological marker locus distributed on 7 of the 10 chromosomes in the genome. Deviati...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1987.44
更新日期:1987-04-01 00:00:00
abstract::The genetic differentiation of populations is usually studied by using the equilibrium theory of Wright's infinite island model. In practice, however, populations are not always in equilibrium, and the number of subpopulations is often very small. To get some insight into the dynamics of genetic differentiation of the...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1986.109
更新日期:1986-10-01 00:00:00
abstract::The conditional average frequency of rare alleles has been shown in simulations to provide a simple and robust estimator of the number of individuals exchanged between local populations in an island model (Nm). This statistic is defined as the average frequency of an allele in those samples in which the allele is pres...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1986.63
更新日期:1986-06-01 00:00:00
abstract::Equilibrium sex ratios have been determined analytically under Wright's island model in order to determine the effect of population structure with limited dispersal. When mating occurs before dispersal, the dispersal rate has little or no effect, and the equilibrium sex ratio remains the same as under complete dispers...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1986.10
更新日期:1986-02-01 00:00:00
abstract::"Parent-offspring conflict" is a theoretical concept proposing that siblings are selected to be slightly more greedy with each other than parents are selected to tolerate. This paper extends a class of previous models of parent-offspring conflict by introducing a new and more realistic dimension to the analysis: the a...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1985.65
更新日期:1985-08-01 00:00:00
abstract::The fixation of major chromosomal rearrangements with a heterozygote disadvantage is modelled as a simple example of Wright's shifting balance process of evolution in a strongly subdivided population. Chromosomal mutations with an inferior heterozygote become fixed in a local population (or deme) by random genetic dri...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1985.43
更新日期:1985-06-01 00:00:00
abstract::Red deer representing the four different European subspecies Cervus elaphus atlanticus, C. e. elaphus, C. e. germanicus, and C. e. scoticus were examined for allozyme variability at 35 enzyme loci. The proportion of polymorphic loci within populations (P) ranged from 0 to 13.8 per cent and the average heterozygosity (...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1983.71
更新日期:1983-12-01 00:00:00
abstract::Heterozygotes are assumed to mate with a frequency that is any general function, f(v), of their population frequency, v. Models are analysed in which the selection that determines the function f(v) acts either on one sex alone or on both sexes equally. The central equilibrium point v* = 1/2 always exists; it is stable...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1981.59
更新日期:1981-08-01 00:00:00
abstract::Recent studies concerning molecular mechanisms of genetic recombination in eukaryotes are reviewed. Since many of these studies have focused on the testable predictions arising from the hybrid DNA theory of genetic recombination, this theory is summarised. Experiments to determine the time of meiotic crossing-over and...
journal_title:Heredity
pub_type: 杂志文章,评审
doi:10.1038/hdy.1977.61
更新日期:1977-10-01 00:00:00
abstract::A model involving a specific pairing of homologous double-stranded nucleic acid molecules is applied to some parts of genetic recombination. The most original features of this application of the model relate to the initiation process, a part of which can be described by a highly compact and symmetrical structure. The ...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1977.39
更新日期:1977-08-01 00:00:00
abstract::The a priori probability of noticeable linkage among all conceivable experiments of the size reported by Mendel cannot reasonably be taken as greater than 24-36 per cent; and therefore, the frequently heard opinion that his chances of encountering linkage were high, approaching 99-4 per cent, appears to be mistaken. ...
journal_title:Heredity
pub_type: 传,历史文章,杂志文章
doi:10.1038/hdy.1977.30
更新日期:1977-04-01 00:00:00
abstract::Fisher's model for the evolution of dominance indicates that the accumulation of dominance modifiers will be accelerated by (1) an increased frequency of the mutant heterozygote, (2) increased selection for the phenotype of the normal homozygote. The model has been criticised by Haldane on the grounds that point (1) i...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1977.13
更新日期:1977-02-01 00:00:00
abstract::Cycloheximide-resistant mutants of Schizosaccharomyces pombe were isolated either as spontaneous mutants or after mutagenic treatment with nitrous acid, UV and N-methyl-N'-nitro-N-nitrosoguanidine (MNNG). Twenty-three spontaneous mutants and 64 induced mutants were analysed genetically. Crosses revealed that at least ...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1976.81
更新日期:1976-10-01 00:00:00
abstract::Cultural transmission may depend on the non-genetic transfer of information from parent to offspring. The consequences of such cultural transmission for continuous variation are investigated theoretically for randomly mating populations. Cultural inheritance may act on genetical and environmental differences between i...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1976.64
更新日期:1976-08-01 00:00:00
abstract::The frequency of B chromosomes has been determined for several stages in the grasshopper life-cycle, over three generations, in three natural populations spanning a steep cline in East Anglia. This has revealed a rise in B frequency in prediapause eggs, a fall during the winter in the embryos and a rise in the early n...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1976.47
更新日期:1976-06-01 00:00:00
abstract::Podisma pedestris exists as both an XO and neoXY form in the Southern French Alps. These chromosome types are shown to be contiguously allopatric and hybrid populations have been located in several places. Hybridisation appears to be occurring freely, but the hybrid zones are quite narrow. In several places the two di...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1975.108
更新日期:1975-12-01 00:00:00
abstract::In the context of frequency-dependent selection, the effect of conditioning the medium, by the previous culture of larvae of a given strain, on the survival of subsequent larvae of the same or different strains was measured. Six strains were sued, some inbred and some lines selected for low or high sternopleural brist...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1975.102
更新日期:1975-12-01 00:00:00
abstract::Populations of Cepaea hortensis have been sampled from an area of 121 sq km on the north slopes of the Brendon Hills, Somerset, and analysed for chiasma frequency. Variation in chiasma frequency is due to variation in a single large bivalent--the A group bivalent. In 12 populations studied during 1973 no association b...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1975.86
更新日期:1975-10-01 00:00:00
abstract::Growth rate of 12 groups of common carp was measured at five experimental environments. Three of the 12 tested groups were strains of the domesticated European race of the common carp, one group was a representative of the Big-Belly Chinese race, and the remaining eight groups were F1 crossbreds among the European str...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1975.42
更新日期:1975-06-01 00:00:00
abstract::A technique for the examination of chromosomes in testicular material in Nucella lapillus is described. The diploid chromosome number varies between 26 and 36. Eight pairs of meatcentric chromosomes are always present and range in size from 9mu to 4mu. Additionally, 10 pairs of acrocentric chromosomes (4mu to 1mu) are...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1975.26
更新日期:1975-04-01 00:00:00
abstract::A model is described for the biometrical analysis of interaction behavioural characteristics. The model is illustrated by analysis of the mating speed of Drosophila pseudoobscura derived from crosses of fast and of slow mating strains generated through artificial selection. ...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1975.1
更新日期:1975-02-01 00:00:00